Title : An ATF/CREB-binding site is essential for cell-specific and inducible transcription of the murine MIP-1 beta cytokine gene.

Pub. Date : 1995 Jan 23

PMID : 7835696






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 One essential cis-regulatory element within the enhancer-like sequence is an activating transcription factor/cAMP response element (CRE)-binding protein (ATF/CREB)-binding site, although the promoter is not cAMP responsive. Cyclic AMP cAMP responsive element binding protein 1 Mus musculus
2 Electrophoretic mobility shift assays and mutational analyses suggest that the promoter site is bound by nuclear protein complexes containing cAMP-independent members of the ATF/CREB family of proteins and c-Jun, and are functionally distinct from the AP1-related TPA-response element (TRE) binding activity. Cyclic AMP cAMP responsive element binding protein 1 Mus musculus