Title : General properties and clinical possibilities of new selective inhibitors of catechol O-methyltransferase.

Pub. Date : 1994 Sep

PMID : 7835624






2 Functional Relationships(s)
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Protein Name
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1 Entacapone, nitecapone and tolcapone are nitrocatechol-type potent COMT inhibitors in vitro (Ki in nanomolar range). entacapone catechol-O-methyltransferase Homo sapiens
2 In man, entacapone, nitecapone and tolcapone all inhibit dose dependently the COMT activity in erythrocytes. entacapone catechol-O-methyltransferase Homo sapiens