Title : Lysophosphatidic acid induction of transforming growth factors alpha and beta: modulation of proliferation and differentiation in cultured human keratinocytes and mouse skin.

Pub. Date : 1995 Jan

PMID : 7813633






4 Functional Relationships(s)
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1 The focus of this work was to determine the effects of LPA on the proliferation and differentiation of early passage cultured human keratinocytes with emphasis on determining if transforming growth factors (TGF), types alpha and beta, are induced by LPA. lysophosphatidic acid transforming growth factor beta 1 Homo sapiens
2 LPA and RA also induced both the active and latent forms TGF beta from cultured keratinocytes. lysophosphatidic acid transforming growth factor beta 1 Homo sapiens
3 The effects of LPA on TGF alpha and TGF beta production by keratinocytes likely have in vivo relevance as concluded from rodent studies involving topical LPA treatments. lysophosphatidic acid transforming growth factor beta 1 Homo sapiens
4 The effects of LPA on TGF alpha and TGF beta production by keratinocytes likely have in vivo relevance as concluded from rodent studies involving topical LPA treatments. lysophosphatidic acid transforming growth factor beta 1 Homo sapiens