Title : Skeletal muscle myosin regulatory light chains conformation affects the papain cleavage of A1 light chains.

Pub. Date : 1994 Dec 14

PMID : 7811699






3 Functional Relationships(s)
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1 In the present study, the influence of magnesium-for-calcium exchange and phosphorylation of regulatory light chain (RLC) on accessibility of myosin and heavy meromyosin alkali light chains (A1) for papain digestion was investigated. Magnesium myosin heavy chain 14 Homo sapiens
2 Exchange of magnesium ions bound to RLCs for calcium ions accelerates the digestion of A1 in the presence of ATP in dephosphorylated myosin, heavy meromyosin, acto-myosin and the acto-heavy meromyosin complex. Magnesium myosin heavy chain 14 Homo sapiens
3 In the absence of ATP the exchange of magnesium ions bound to RLCs for calcium ions delays the digestion of A1 in the acto-myosin complex. Magnesium myosin heavy chain 14 Homo sapiens