Title : Proteolysis of A beta peptide from Alzheimer disease brain by gelatinase A.

Pub. Date : 1994 Dec 30

PMID : 7811262






1 Functional Relationships(s)
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1 It has been recently reported that the 72 kDa proteolytic enzyme gelatinase A/type IV collagenase/matrix metalloproteinase 2 (MMP2) hydrolyzed the Lys 16-Leu 17 peptide bond of a synthetic decapeptide (YEVHHQKLVFF) representing the soluble A beta sequence of amino acid residues 10-20. Leucine amyloid beta precursor protein Homo sapiens