Pub. Date : 1994 Jul
PMID : 7801766
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Incubation of aortic rings in the absence of extracellular Ca2+ or in the presence of the Ca2+ channel blocker nifedipine (100 nmol.L-1) greatly attenuated ET-1-induced vasoconstriction. | Nifedipine | endothelin 1 | Rattus norvegicus |
| 2 | Therefore, ET-1 may utilize at least 2 signal transduction mechanisms, one involving the opening of nifedipine-sensitive Ca2+ channels and the other involving the elevation of cAMP levels, to produce the unusually slow-developing and stable vasoconstrictions in rat aortae. | Nifedipine | endothelin 1 | Rattus norvegicus |