Pub. Date : 1995 Jul 1
PMID : 7796393
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Transcriptional activation of the proto-oncogene c-jun by asbestos and H2O2 is directly related to increased proliferation and transformation of tracheal epithelial cells. | Hydrogen Peroxide | Jun proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |
| 2 | To examine whether asbestos or H2O2 induced transcription of c-jun, we transiently transfected HTE cells with a plasmid containing a fragment of the c-jun promoter coupled to a luciferase reporter gene. | Hydrogen Peroxide | Jun proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |
| 3 | These results demonstrate that asbestos and H2O2 activate AP-1-dependent gene transcription. | Hydrogen Peroxide | Jun proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |