Title : A direct role of transcription factor E2F in c-myc gene expression during granulocytic and macrophage-like differentiation of HL60 cells.

Pub. Date : 1995 Mar

PMID : 7794791






1 Functional Relationships(s)
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1 HL60 cells are able to differentiate into a granulocytic lineage by prolonged exposure to retinoids and into a macrophage-like lineage by exposure to tumor promoter 12-O-tetradecanoylphorbol 13-acetate, with a rapid decrease of c-myc gene expression. Tetradecanoylphorbol Acetate MYC proto-oncogene, bHLH transcription factor Homo sapiens