Title : Antagonist properties of LY 165,163 at pre- and postsynaptic dopamine D2, D3 and D1 receptors: modulation of agonist actions at 5-HT1A receptors in vivo.

Pub. Date : 1995 Jun

PMID : 7791116






1 Functional Relationships(s)
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1 Consistently with antagonist properties at postsynaptic D2 receptors, in unilateral substantia nigra-lesioned rats, the rotation elicited by the D2 agonist quinpirole was potently blocked by LY 165,163, whereas that elicited by the D1 agonist SKF 38393 was only weakly inhibited. 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine solute carrier family 3 member 1 Rattus norvegicus