Title : Differential regulation of a multipromoter gene. Selective 12-O-tetradecanoylphorbol-13-acetate induction of a single transcription start site in the HMG-I/Y gene.

Pub. Date : 1995 Jun 9

PMID : 7775485






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Selective 12-O-tetradecanoylphorbol-13-acetate induction of a single transcription start site in the HMG-I/Y gene. Tetradecanoylphorbol Acetate high mobility group AT-hook 1 Homo sapiens
2 The human HMG-I/Y gene, encoding the non-histone "high mobility group" proteins HMG-I and HMG-Y, is transcriptionally activated in human K562 erythroleukemia cells by treatment with 12-O-tetradecanoylphorbol-13-acetate (TPA). Tetradecanoylphorbol Acetate high mobility group AT-hook 1 Homo sapiens
3 The human HMG-I/Y gene, encoding the non-histone "high mobility group" proteins HMG-I and HMG-Y, is transcriptionally activated in human K562 erythroleukemia cells by treatment with 12-O-tetradecanoylphorbol-13-acetate (TPA). Tetradecanoylphorbol Acetate high mobility group AT-hook 1 Homo sapiens
4 In this report, we show that transcriptional activation of the HMG-I/Y gene is dependent on protein synthesis and is an early event (2 h after induction) in the TPA-mediated differentiation process. Tetradecanoylphorbol Acetate high mobility group AT-hook 1 Homo sapiens