Title : Ligand-dependent antagonism by retinoid X receptors of inhibitory thyroid hormone response elements.

Pub. Date : 1995 Jun 9

PMID : 7775449






2 Functional Relationships(s)
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1 Cotransfection of an RXR-alpha but not a retinoic acid receptor-alpha expression vector further antagonizes thyroid hormone inhibition, but only in the presence of 9-cis RA. Radium retinoid X receptor alpha Homo sapiens
2 A model is proposed whereby monomeric T3R is removed from a nTRE by RXR occupied by its ligand 9-cis RA. Radium retinoid X receptor alpha Homo sapiens