Title : Regulation of interleukin-8 gene expression by all-trans retinoic acid.

Pub. Date : 1995 May 25

PMID : 7763262






7 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Regulation of interleukin-8 gene expression by all-trans retinoic acid. Tretinoin C-X-C motif chemokine ligand 8 Homo sapiens
2 We have studied the relationship between interleukin-8 (IL-8) and interleukin-1 alpha (IL-1 alpha) release after stimulation with all-trans retinoic acid (ATRA) and tumor necrosis factor-alpha (TNF-alpha) in the human epithelial ovarian cancer cell line HOC-7. Tretinoin C-X-C motif chemokine ligand 8 Homo sapiens
3 We have studied the relationship between interleukin-8 (IL-8) and interleukin-1 alpha (IL-1 alpha) release after stimulation with all-trans retinoic acid (ATRA) and tumor necrosis factor-alpha (TNF-alpha) in the human epithelial ovarian cancer cell line HOC-7. Tretinoin C-X-C motif chemokine ligand 8 Homo sapiens
4 We have studied the relationship between interleukin-8 (IL-8) and interleukin-1 alpha (IL-1 alpha) release after stimulation with all-trans retinoic acid (ATRA) and tumor necrosis factor-alpha (TNF-alpha) in the human epithelial ovarian cancer cell line HOC-7. Tretinoin C-X-C motif chemokine ligand 8 Homo sapiens
5 We have studied the relationship between interleukin-8 (IL-8) and interleukin-1 alpha (IL-1 alpha) release after stimulation with all-trans retinoic acid (ATRA) and tumor necrosis factor-alpha (TNF-alpha) in the human epithelial ovarian cancer cell line HOC-7. Tretinoin C-X-C motif chemokine ligand 8 Homo sapiens
6 Both IL-1 alpha and IL-8 protein release were enhanced by treatment with ATRA and TNF-alpha after 48 h exposure. Tretinoin C-X-C motif chemokine ligand 8 Homo sapiens
7 Blocking of IL-1 alpha activity in HOC-7 cells with either IL-1 receptor antagonist (IL-1ra) or a neutralizing antibody directed against IL-1 alpha resulted in a dose-dependent decrease of IL-8 release by ATRA, TNF-alpha and IL-1 alpha treated HOC-7 cells. Tretinoin C-X-C motif chemokine ligand 8 Homo sapiens