Title : Two heparin-binding domains are present on the collagenic tail of asymmetric acetylcholinesterase.

Pub. Date : 1995 May 12

PMID : 7744733






4 Functional Relationships(s)
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1 The collagen-tailed form of acetylcholinesterase (AChE) binds to heparin and heparan sulfate proteoglycans. Heparin acetylcholinesterase (Cartwright blood group) Homo sapiens
2 We have employed synthetic peptides corresponding to the central collagenic region of the tail of AChE, to identify the heparin-binding domains of the tail of asymmetric AChE. Heparin acetylcholinesterase (Cartwright blood group) Homo sapiens
3 We have employed synthetic peptides corresponding to the central collagenic region of the tail of AChE, to identify the heparin-binding domains of the tail of asymmetric AChE. Heparin acetylcholinesterase (Cartwright blood group) Homo sapiens
4 Peptides containing such sequences (P-(145-159) and P-(249-262)) were able to release asymmetric AChE bound to heparin-agarose. Heparin acetylcholinesterase (Cartwright blood group) Homo sapiens