Title : Expression of human cyclophilin-40 and the effect of the His141-->Trp mutation on catalysis and cyclosporin A binding.

Pub. Date : 1995 Apr 1

PMID : 7744028






1 Functional Relationships(s)
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1 The weak affinity of CyP-40 for cyclosporin A was postulated to arise from a histidine residue that replaces a tryptophan residue critical for cyclosporin A binding and highly conserved in other cyclophilins that have high affinity for cyclosporin A. Histidine peptidylprolyl isomerase D Homo sapiens