Title : Distribution of receptors mediating phosphoinositide hydrolysis in cultured human umbilical artery smooth muscle and endothelial cells.

Pub. Date : 1995 Mar 30

PMID : 7741756






1 Functional Relationships(s)
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1 In human umbilical artery smooth muscle cells, histamine (EC50 16 microM), bradykinin (EC50 4.5 nM), 5-HT (EC50 0.7 microM) and carbachol (EC50 21 microM) produced substantial effects (> 20% of the response to 1 mM histamine) on inositol phospholipid hydrolysis while ATP (1 mM) and thrombin (1 U/mL) were much less effective. Phosphatidylinositols kininogen 1 Homo sapiens