Title : Overexpression of apolipoprotein E prevents development of diabetic hyperlipidemia in transgenic mice.

Pub. Date : 1995 May

PMID : 7729619






1 Functional Relationships(s)
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1 Induction of apoE remarkably reduced the development of hyperlipidemia in diabetic transgenic mice compared with diabetic nontransgenic mice (plasma cholesterol level: 4.55 +/- 1.32 vs. 3.31 +/- 0.47 mmol/l [176 +/- 51 vs. 128 +/- 18 mg/dl], P < 0.01, and plasma triglyceride level: 0.82 +/- 0.29 vs. 0.17 +/- 0.11 mmol/l [73 +/- 26 vs. 15 +/- 10 mg/dl], P < 0.01). Cholesterol apolipoprotein E Mus musculus