Pub. Date : 1995 Jan
PMID : 7720517
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | When budesonide (10 microM) was incubated with human liver microsomes in the presence of compounds known to interact with different isoforms or subfamilies of CYP, ketoconazole was found to be the strongest inhibitor of budesonide metabolism (IC50: approximately 0.1 microM) followed by troleandomycin (IC50: approximately 1 microM), erythromycin, and cyclosporin, all substances known to interact with CYP3A isoenzymes. | Ketoconazole | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |