Title : Improved brain delivery and in vitro activity of zidovudine through the use of a redox chemical delivery system.

Pub. Date : 1995 Feb

PMID : 7718185






2 Functional Relationships(s)
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Protein Name
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1 ZDV-CDS at 0.5 microM was 80% more effective than ZDV in suppressing p24 production in a lymphocyte culture infected with 6000 median tissue culture infective doses (TCID50) of the HIV N1T strain and 50% more effective at 0.05 microM. Zidovudine transmembrane p24 trafficking protein 2 Homo sapiens
2 Finally, while ZDV (at 0.5 microM) is not active in reducing viral replication in an SKNMC neural cell line, the ZDV-CDS complex significantly suppressed p24 synthesis. Zidovudine transmembrane p24 trafficking protein 2 Homo sapiens