Title : Dibutyryl cyclic AMP protects Corynebacterium parvum-treated mice against lipopolysaccharide-induced lethal toxicity.

Pub. Date : 1995 Apr 15

PMID : 7704897






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Pretreatment of the C. parvum-induced macrophages with DBcAMP significantly inhibited the TNF alpha production in response to LPS and decreased the susceptibility to LPS-induced cytotoxicity in vitro. Bucladesine tumor necrosis factor Mus musculus
2 Similar to the findings seen in in vitro experiments, in vivo administration with DBcAMP significantly inhibited the TNF alpha release in the sera of C. parvum-treated mice after LPS challenge and consequently decreased the susceptibility to LPS-induced shock. Bucladesine tumor necrosis factor Mus musculus