Title : Mathematical modelling of the enteric nervous network. 4. Analysis of adrenergic transmission.

Pub. Date : 1995 Jan

PMID : 7704341






1 Functional Relationships(s)
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1 The results of numerical simulation show that: the addition of drugs that inhibit neuronal uptake and catechol-O-methyltransferase cause the augmentation of noradrenaline action on post-synaptic structures and an increase in the amplitude of the generated inhibitory post-synaptic potential (IPSP); treatment with adrenergic antagonists reduces the amplitude of IPSP; decrease in the concentration of extracellular Ca2+ ions and application of TTX abolish the post-synaptic response. Norepinephrine catechol-O-methyltransferase Homo sapiens