Pub. Date : 1994 Dec
PMID : 7704038
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Metabolism of diazepam was studied in vitro to identify the forms of cytochrome P450 (CYP) responsible for N-demethylation (nordazepam formation) and 3-hydroxylation (temazepam formation), using liver microsomes obtained from extensive (EM) and poor metabolizers (PM) for S-mephenytoin 4"-hydroxylation. | Mephenytoin | cytochrome P450 family 4 subfamily F member 3 | Homo sapiens |
| 2 | Metabolism of diazepam was studied in vitro to identify the forms of cytochrome P450 (CYP) responsible for N-demethylation (nordazepam formation) and 3-hydroxylation (temazepam formation), using liver microsomes obtained from extensive (EM) and poor metabolizers (PM) for S-mephenytoin 4"-hydroxylation. | Mephenytoin | cytochrome P450 family 4 subfamily F member 3 | Homo sapiens |