Title : [Chemical carcinogenesis and cytochrome P450: carcinogenic aromatic amine-induced P450 and hepatocarcinogenic susceptibility to the aromatic amine in the rodent].

Pub. Date : 1995 Jan

PMID : 7699577






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Carcinogenic aromatic amines such as heterocyclic aromatic amines and aminoazo dyes induced predominantly cytochrome P450IA2 (CYP1A2), which is responsible for the mutagenic activation and N-hydroxylation of the amines in the rodent. Amines cytochrome P450 family 1 subfamily A member 2 Homo sapiens