Title : Use of cloned and expressed human liver UDP-glucuronosyltransferases for analysis of drug glucuronide formation and assessment of drug toxicity.

Pub. Date : 1994 Nov

PMID : 7698078






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 UGT-HP1 exhibited a limited substrate specificity for planar phenolic compounds, whereas UGT-HP4 was more accepting of nonplanar phenols, anthraquinones, flavones, alphatic alcohols, aromatic carboxylic acids, steroids and many drugs of varied structure. Anthraquinones UDP glucuronosyltransferase family 1 member A complex locus Homo sapiens
2 UGT-HP1 exhibited a limited substrate specificity for planar phenolic compounds, whereas UGT-HP4 was more accepting of nonplanar phenols, anthraquinones, flavones, alphatic alcohols, aromatic carboxylic acids, steroids and many drugs of varied structure. Anthraquinones UDP glucuronosyltransferase family 1 member A complex locus Homo sapiens