Title : Transgenic expression of human MGMT protects against azoxymethane-induced aberrant crypt foci and G to A mutations in the K-ras oncogene of mouse colon.

Pub. Date : 1995 Mar

PMID : 7697797






1 Functional Relationships(s)
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1 In this study we evaluated the ability of transgenic overexpression of MGMT in the colon to protect mice from the development of azoxymethane(AOM)-induced aberrant crypt foci (ACF) and mutations in K-ras. Azoxymethane O-6-methylguanine-DNA methyltransferase Mus musculus