Pub. Date : 1995 Jan 17
PMID : 7695204
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | To clarify the mechanism that causes elevation of plasma fibrinogen levels in diabetes, we examined the effect of high concentration of glucose and/or advanced glycosylation end products (AGEs) on the production of interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha) by human monocytes. | Glucose | interleukin 6 | Homo sapiens |
| 2 | IL-6 and TNF-alpha levels of culture supernatants incubated with 22 mM or 33 mM glucose showed considerable increase over basal levels incubated with 11 mM glucose, whereas those levels incubated with high concentration of mannitol showed no increase. | Glucose | interleukin 6 | Homo sapiens |
| 3 | IL-6 and TNF-alpha levels of culture supernatants incubated with 22 mM or 33 mM glucose showed considerable increase over basal levels incubated with 11 mM glucose, whereas those levels incubated with high concentration of mannitol showed no increase. | Glucose | interleukin 6 | Homo sapiens |
| 4 | Our serial observation with treatment for lowering glucose levels showed that the diabetics with decreasing plasma fibrinogen levels also showed decrease in plasma IL-6 levels. | Glucose | interleukin 6 | Homo sapiens |
| 5 | In this study, we revealed the effect of glucose and AGEs on the production of IL-6 or TNF-alpha by human monocytes. | Glucose | interleukin 6 | Homo sapiens |