Pub. Date : 1993 Sep
PMID : 7692744
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The S6 monoclonal antibody to somatostatin, but not control antibodies, enhanced gastrin-stimulated histamine release. | Histamine | gastrin | Canis lupus familiaris |
| 2 | In the presence of S6, the somatostatin analogue SMS-201-995 (10(-7) M) inhibited gastrin-stimulated histamine release by 95%. | Histamine | gastrin | Canis lupus familiaris |
| 3 | Thus somatostatin selectively inhibited the gastrin-responsive histamine pool, which presumably is stored in oxyntic mucosal endocrine cells. | Histamine | gastrin | Canis lupus familiaris |
| 4 | Furthermore, enhancement of gastrin-stimulated histamine release by immunoneutralization of somatostatin indicates an important role for endogenous somatostatin as a paracrine inhibitor of non-mast cell histamine release. | Histamine | gastrin | Canis lupus familiaris |
| 5 | Furthermore, enhancement of gastrin-stimulated histamine release by immunoneutralization of somatostatin indicates an important role for endogenous somatostatin as a paracrine inhibitor of non-mast cell histamine release. | Histamine | gastrin | Canis lupus familiaris |