Pub. Date : 1993 Mar-Apr
PMID : 7682247
9 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The level of activated HSF binding to HSE was higher in cells treated with low doses (1 ng/ml) of bleomycin than in cells treated with 1 or 25 micrograms/ml bleomycin. | Bleomycin | interleukin 6 | Homo sapiens |
| 2 | The binding of heat shock factor (HSF) in response to heat and varying concentrations of bleomycin in the four cell lines was examined using a gel shift assay and a synthetic heat shock element (HSE). | Bleomycin | interleukin 6 | Homo sapiens |
| 3 | The binding of heat shock factor (HSF) in response to heat and varying concentrations of bleomycin in the four cell lines was examined using a gel shift assay and a synthetic heat shock element (HSE). | Bleomycin | interleukin 6 | Homo sapiens |
| 4 | Heat (45 degrees C, 10 min) and exposure to 1 micrograms/ml bleomycin for 1 h at 37 degrees C induced similar levels of HSF binding in all four cell lines. | Bleomycin | interleukin 6 | Homo sapiens |
| 5 | We also examined if bleomycin dose and the length of recovery from bleomycin treatment affected the induction of HSF binding. | Bleomycin | interleukin 6 | Homo sapiens |
| 6 | We also examined if bleomycin dose and the length of recovery from bleomycin treatment affected the induction of HSF binding. | Bleomycin | interleukin 6 | Homo sapiens |
| 7 | The level of activated HSF binding to HSE was higher in cells treated with low doses (1 ng/ml) of bleomycin than in cells treated with 1 or 25 micrograms/ml bleomycin. | Bleomycin | interleukin 6 | Homo sapiens |
| 8 | The amount of activated HSF was directly proportional to the time elapsed since bleomycin treatment. | Bleomycin | interleukin 6 | Homo sapiens |
| 9 | Our results therefore indicate no difference between CHO and its bleomycin-sensitive derivatives in the ability to initiate the heat shock response as determined by the production of activated HSF in response to either heat or bleomycin. | Bleomycin | interleukin 6 | Homo sapiens |