Title : Antiplatelet effects of nitroglycerin in healthy subjects and in patients with stable angina pectoris.

Pub. Date : 1993 Mar

PMID : 7681498






1 Functional Relationships(s)
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1 Platelets from patients with angina pectoris were 100-fold less responsive to the cyclic GMP-increasing and disaggregating effects of NTG in vitro, which, together with increased aggregability, could imply reduced platelet sensitivity to endogenous sources of nitric oxide (NO) in vivo. Nitroglycerin 5'-nucleotidase, cytosolic II Homo sapiens