Title : Stereoselective renal effects of the loop diuretic ozolinone in the anesthetized dog.

Pub. Date : 1995 Jun

PMID : 7675125






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The inhibition of prostaglandin synthesis (indomethacin or meclofenamate) prevented renin hypersecretion in response to (-)-ozolinone and modified its salidiuretic effects but had no effect on the vascular response. Prostaglandins renin Canis lupus familiaris
2 Our results demonstrate that the loop diuretic, ozolinone, induces stereoselective and prostaglandin-dependent renin secretion, which is involved in the regulation of intra-renal hemodynamics. Prostaglandins renin Canis lupus familiaris