Title : Pronounced activation of protein kinase C, ornithine decarboxylase and c-jun proto-oncogene by paraquat-generated active oxygen species in WI-38 human lung cells.

Pub. Date : 1995 Aug 31

PMID : 7662713






1 Functional Relationships(s)
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1 We therefore propose that superoxide anion (O2- and H2O2 generated by PQ could activate PKC and lead to induction of c-jun gene expression; on the other hand, O2- and .OH might trigger other kinase pathways to elevate ODC activity. Hydrogen Peroxide Jun proto-oncogene, AP-1 transcription factor subunit Homo sapiens