Title : 5-Hydroxytryptophan: an absorption and fluorescence probe which is a conservative replacement for [A14 tyrosine] in insulin.

Pub. Date : 1995 May

PMID : 7662110






3 Functional Relationships(s)
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1 5-Hydroxytryptophan: an absorption and fluorescence probe which is a conservative replacement for [A14 tyrosine] in insulin. 5-Hydroxytryptophan insulin Homo sapiens
2 We describe the synthesis of an insulin analog where A14 tyrosine is replaced by a tryptophan analog, 5-hydroxytryptophan. 5-Hydroxytryptophan insulin Homo sapiens
3 This insulin is spectrally enhanced since 5-hydroxytryptophan has an absorption band above 300 nm which is at lower energies than the absorption of tryptophan. 5-Hydroxytryptophan insulin Homo sapiens