Title : Synthesis and evaluation of 5-amino-5,6,7,8-tetrahydroquinolinones as potential agents for the treatment of Alzheimer's disease.

Pub. Date : 1995 Sep 1

PMID : 7658452






1 Functional Relationships(s)
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1 They inhibit acetylcholinesterase in vitro, and many are active in vivo in reversing a scopolamine-induced impairment of 24 h memory in a passive avoidance paradigm. Scopolamine acetylcholinesterase (Cartwright blood group) Homo sapiens