Title : Allosteric control of acetylcholinesterase catalysis by fasciculin.

Pub. Date : 1995 Sep 1

PMID : 7657613






1 Functional Relationships(s)
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1 Analysis of the kinetics of acylation by organophosphates and conjugation by trifluoroacetophenones, along with deconstruction of the kinetic constants for carboxyl esters, suggests that AChE inhibition by fasciculin arises from reductions of both the commitment to catalysis and diffusional entry of substrate into the gorge. Organophosphates acetylcholinesterase (Cartwright blood group) Homo sapiens