Pub. Date : 1995 May 26
PMID : 7656409
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | These retinoic acid-induced increases in GAP43/B50 and neurite outgrowth, and decreases in N-myc and c-myc, were reversed dose-dependently by alcohol (0-0.5%). | Tretinoin | MYCN proto-oncogene, bHLH transcription factor | Homo sapiens |
2 | Conversely, the adverse effects of 0.25% alcohol on neurite extension, GAP43/B50, N-myc, and c-myc were prevented by 15 and 45 nM retinoic acid. | Tretinoin | MYCN proto-oncogene, bHLH transcription factor | Homo sapiens |
3 | These results suggest that inhibition of neuronal differentiation by alcohol and prevention of such effects by retinoic acid are related to changes in GAP43/B50, N-myc and c-myc. | Tretinoin | MYCN proto-oncogene, bHLH transcription factor | Homo sapiens |