Title : Adenosine activates A2 receptors to inhibit neutrophil adhesion and injury to isolated cardiac myocytes.

Pub. Date : 1995 Sep 1

PMID : 7650388






1 Functional Relationships(s)
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1 Neutrophil-myocyte adhesion was inhibited by acadesine (IC50 = 12 +/- 2 microM) also via an adenosine-dependent mechanism because it was blocked by 1,3-dimethyl-1-propylxanthine or adenosine deaminase, an enzyme that degrades any adenosine that is formed. acadesine adenosine deaminase Canis lupus familiaris