Pub. Date : 1995 May
PMID : 7647987
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | EGF responses either in the presence or absence of ITF were also significantly reduced (84% and 66% respectively) by the cyclo-oxygenase inhibitor, piroxicam, therefore implicating prostaglandins as mediators of EGF-stimulated anion secretion. | Prostaglandins | epidermal growth factor | Homo sapiens |
| 2 | EGF responses either in the presence or absence of ITF were also significantly reduced (84% and 66% respectively) by the cyclo-oxygenase inhibitor, piroxicam, therefore implicating prostaglandins as mediators of EGF-stimulated anion secretion. | Prostaglandins | epidermal growth factor | Homo sapiens |
| 3 | We conclude that in confluent Col-29 epithelia, basolateral EGF stimulates a predominantly prostaglandin-dependent increase in Cl- secretion that is enhanced by basolateral ITF, and that these two peptides may interact in normal and damaged mucosa to alter the local apical solute and fluid environment. | Prostaglandins | epidermal growth factor | Homo sapiens |