Title : Phenobarbital induction of CYP2B1, CYP2B2, and CYP3A1 in rat liver: genetic differences in a common regulatory mechanism.

Pub. Date : 1995 Aug 20

PMID : 7646073






1 Functional Relationships(s)
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1 Partial depletion of thyroid hormone and growth hormone levels by methimazole treatment was equally as effective as hypophysectomy in elevating phenobarbital-induced levels of CYP2B1, CYP2B2, and CYP3A1 in Wistar Furth rats, while the Fischer strain was unaffected. Methimazole cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 Rattus norvegicus