Title : The human papilloma virus 16E6 gene sensitizes human mammary epithelial cells to apoptosis induced by DNA damage.

Pub. Date : 1995 Aug 15

PMID : 7644500






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 In contrast, two HPV immortalized cell lines in which p53 protein was destroyed by E6-modulated ubiquitinylation were highly sensitive to apoptosis induced by MMC. Mitomycin tumor protein p53 Homo sapiens
2 Thus, HPV 16E6 can sensitize mammary epithelial cells to MMC-induced apoptosis via a p53- and p21-independent pathway. Mitomycin tumor protein p53 Homo sapiens