Title : Detection of P-glycoprotein with a rapid flow cytometric functional assay using Fluo-3: evaluation of sensitivity, specificity and feasibility in multiparametric analysis.

Pub. Date : 1995 Aug

PMID : 7643631






1 Functional Relationships(s)
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Protein Name
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1 Downmodulation of Pgp function in these cell lines could be demonstrated with different substances (verapamil, vinblastine, trifluoperazine, cyclosporin A, progesterone and quinidine) and was proven to be consistently higher in the vinblastine selected cells than in their non-selected drug sensitive counterparts. Progesterone ATP binding cassette subfamily B member 1 Homo sapiens