Title : Selection of a suppressor mutation that restores affinity of an oligonucleotide inhibitor for thrombin using in vitro genetics.

Pub. Date : 1995 Aug 18

PMID : 7642616






1 Functional Relationships(s)
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1 In contrast, aptamers selected against R70E thrombin were able to bind and inhibit both wild-type and R70E thrombins, and displayed potassium-independent inhibition. Potassium coagulation factor II, thrombin Homo sapiens