Pub. Date : 1995 Aug 11
PMID : 7642556
12 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We investigated the mechanisms by which H2O2 increases intercellular adhesion molecule 1 (ICAM-1; CD54) expression in endothelial cells. | Hydrogen Peroxide | intercellular adhesion molecule 1 | Homo sapiens |
| 2 | We investigated the mechanisms by which H2O2 increases intercellular adhesion molecule 1 (ICAM-1; CD54) expression in endothelial cells. | Hydrogen Peroxide | intercellular adhesion molecule 1 | Homo sapiens |
| 3 | We investigated the mechanisms by which H2O2 increases intercellular adhesion molecule 1 (ICAM-1; CD54) expression in endothelial cells. | Hydrogen Peroxide | intercellular adhesion molecule 1 | Homo sapiens |
| 4 | The H2O2-induced increase in ICAM-1 mRNA was inhibited by actinomycin D, by the antioxidant N-acetylcysteine, and by 3-amino-benzamide (which blocks oxidant-induced AP-1 activity), but not by pyrrolidine dithiocarbamate (which blocks oxidant-induced NF-kappa B activity). | Hydrogen Peroxide | intercellular adhesion molecule 1 | Homo sapiens |
| 5 | Nuclear run-on and transient transfections of ICAM-1 promoter constructs indicated that H2O2 stimulated ICAM-1 gene transcription by activation of a distinct region of the ICAM-1 promoter. | Hydrogen Peroxide | intercellular adhesion molecule 1 | Homo sapiens |
| 6 | Nuclear run-on and transient transfections of ICAM-1 promoter constructs indicated that H2O2 stimulated ICAM-1 gene transcription by activation of a distinct region of the ICAM-1 promoter. | Hydrogen Peroxide | intercellular adhesion molecule 1 | Homo sapiens |
| 7 | Nuclear run-on and transient transfections of ICAM-1 promoter constructs indicated that H2O2 stimulated ICAM-1 gene transcription by activation of a distinct region of the ICAM-1 promoter. | Hydrogen Peroxide | intercellular adhesion molecule 1 | Homo sapiens |
| 8 | Mutation of the 16-base pair repeats within the ICAM-1 promoter prevented H2O2-induced DNA binding activity, and their deletion abrogated the H2O2-induced transcriptional activity. | Hydrogen Peroxide | intercellular adhesion molecule 1 | Homo sapiens |
| 9 | Mutation of the 16-base pair repeats within the ICAM-1 promoter prevented H2O2-induced DNA binding activity, and their deletion abrogated the H2O2-induced transcriptional activity. | Hydrogen Peroxide | intercellular adhesion molecule 1 | Homo sapiens |
| 10 | The results indicate that H2O2 activates ICAM-1 transcription through AP-1/Ets elements within the ICAM-1 promoter, which are distinct from NF-kappa B-mediated ICAM-1 expression induced by TNF alpha. | Hydrogen Peroxide | intercellular adhesion molecule 1 | Homo sapiens |
| 11 | The results indicate that H2O2 activates ICAM-1 transcription through AP-1/Ets elements within the ICAM-1 promoter, which are distinct from NF-kappa B-mediated ICAM-1 expression induced by TNF alpha. | Hydrogen Peroxide | intercellular adhesion molecule 1 | Homo sapiens |
| 12 | The results indicate that H2O2 activates ICAM-1 transcription through AP-1/Ets elements within the ICAM-1 promoter, which are distinct from NF-kappa B-mediated ICAM-1 expression induced by TNF alpha. | Hydrogen Peroxide | intercellular adhesion molecule 1 | Homo sapiens |