Title : NF-kappa B transcription factor activation by hydrogen peroxide can be decreased by 2,3-dihydroxybenzoic acid and its ethyl ester derivative.

Pub. Date : 1995 Aug 1

PMID : 7639530






5 Functional Relationships(s)
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1 NF-kappa B transcription factor activation by hydrogen peroxide can be decreased by 2,3-dihydroxybenzoic acid and its ethyl ester derivative. Hydrogen Peroxide nuclear factor kappa B subunit 1 Homo sapiens
2 Reactive oxygen species like hydrogen peroxide (H2O2) have been shown to serve as messengers in the induction of NF-kappa B and, hence, in the activation and replication of human immunodeficiency virus type 1 (HIV-1) in human cells. Hydrogen Peroxide nuclear factor kappa B subunit 1 Homo sapiens
3 Reactive oxygen species like hydrogen peroxide (H2O2) have been shown to serve as messengers in the induction of NF-kappa B and, hence, in the activation and replication of human immunodeficiency virus type 1 (HIV-1) in human cells. Hydrogen Peroxide nuclear factor kappa B subunit 1 Homo sapiens
4 The treatment of monocytes with increasing amounts of H2O2 (from 0 to 3 mM) leads to the nuclear induction of NF-kappa B which is dose dependently inhibited by both DHB and DHB-EE. Hydrogen Peroxide nuclear factor kappa B subunit 1 Homo sapiens
5 Addition of ferric ions to DHB only partially restores the NF-kappa B induction by H2O2, while this effect is almost completely restored by ferric ion addition to DHB-EE. Hydrogen Peroxide nuclear factor kappa B subunit 1 Homo sapiens