Title : Cholinesterase inhibitors proposed for treating dementia in Alzheimer's disease: selectivity toward human brain acetylcholinesterase compared with butyrylcholinesterase.

Pub. Date : 1995 Aug

PMID : 7636741






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The purpose of this study was to determine the selectivity of physostigmine, metrifonate, methanesulfonyl fluoride and tetrahydroaminoacridine (tacrine) toward AChE as compared with butyrylcholinesterase (BChE) in human cortex. Trichlorfon acetylcholinesterase (Cartwright blood group) Homo sapiens
2 Metrifonate was found to inhibit BChE more than AChE. Trichlorfon acetylcholinesterase (Cartwright blood group) Homo sapiens