Title : Association of the interferon-dependent tyrosine kinase Tyk-2 with the hematopoietic cell phosphatase.

Pub. Date : 1995 Aug 4

PMID : 7629131






1 Functional Relationships(s)
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1 We report that Tyk-2 forms stable complexes with the SH2-containing hematopoietic cell phosphatase (HCP) in several hematopoietic cell lines in vivo, and that the IFN alpha-induced tyrosine-phosphorylated form of Tyk-2 is a substrate for the phosphatase activity of HCP in in vitro assays. Tyrosine interferon alpha 1 Homo sapiens