Title : Drug-stimulated ATPase activity of the human P-glycoprotein.

Pub. Date : 1995 Feb

PMID : 7629050






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The human multidrug resistance protein, or P-glycoprotein (Pgp), exhibits a high-capacity drug-dependent ATP hydrolytic activity that is a direct reflection of its drug transport capability. Adenosine Triphosphate ATP binding cassette subfamily B member 1 Homo sapiens
2 The human multidrug resistance protein, or P-glycoprotein (Pgp), exhibits a high-capacity drug-dependent ATP hydrolytic activity that is a direct reflection of its drug transport capability. Adenosine Triphosphate ATP binding cassette subfamily B member 1 Homo sapiens
3 Many of the drugs stimulate the Pgp ATPase activity, but certain drugs bind tightly to the drug-binding site of the Pgp without eliciting ATP hydrolysis. Adenosine Triphosphate ATP binding cassette subfamily B member 1 Homo sapiens
4 Many of the drugs stimulate the Pgp ATPase activity, but certain drugs bind tightly to the drug-binding site of the Pgp without eliciting ATP hydrolysis. Adenosine Triphosphate ATP binding cassette subfamily B member 1 Homo sapiens