Title : 5-Ethoxy-2'-deoxyuridine, a novel substrate for thymidine phosphorylase, potentiates the antitumor activity of 5-fluorouracil when used in combination with interferon, an inducer of thymidine phosphorylase expression.

Pub. Date : 1995 Aug 15

PMID : 7627962






1 Functional Relationships(s)
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1 A comparable antitumor effect was also found when a related nucleoside analogue, 5-propynyloxy-2"-deoxyuridine, was used with FUra+IFN, and it also showed modulating activity when used with only FUra. Nucleosides interferon alpha 1 Homo sapiens