Title : Identification of an origin of bidirectional DNA replication in the ubiquitously expressed mammalian CAD gene.

Pub. Date : 1995 Aug

PMID : 7623808






2 Functional Relationships(s)
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Compound Name
Protein Name
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1 DNA replication initiates within this region in the single-copy CAD gene in Syrian baby hamster kidney cells and in the large chromosomal amplicons that were generated after selection with N-phosphonacetyl-L-aspartate, a specific inhibitor of CAD. sparfosic acid CAD protein Mesocricetus auratus
2 DNA synthesis also initiates within this OBR in autonomously replicating extrachromosomal amplicons (CAD episomes) located in an N-phosphonacetyl-L-aspartate-resistant clone (5P20) of CHOK1 cells. sparfosic acid CAD protein Mesocricetus auratus