Title : Study of the roles of Arg-104 and Arg-225 in the 2-kinase domain of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase by site-directed mutagenesis.

Pub. Date : 1995 Jul 1

PMID : 7619077






1 Functional Relationships(s)
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1 In recombinant rat muscle PFK-2/FBPase-2, mutation of Arg-104 to Ser increased the Km for Fru-6-P 60-fold, increased the IC50 of citrate, increased the Vmax. Citric Acid 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 Rattus norvegicus