Title : Molecular cloning and characterization of a novel gene of Candida albicans, CDR1, conferring multiple resistance to drugs and antifungals.

Pub. Date : 1995 Mar

PMID : 7614555






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Transformation by CDR1 of a PDR5-disrupted host hypersensitive to cycloheximide and chloramphenicol resulted in resistance to cycloheximide, chloramphenicol and other drugs, such as the antifungal miconazole, with collateral hypersensitivity to oligomycin, nystatin and 2,4 dinitrophenol. Cycloheximide ATP-binding cassette multidrug transporter PDR5 Saccharomyces cerevisiae S288C
2 Transformation by CDR1 of a PDR5-disrupted host hypersensitive to cycloheximide and chloramphenicol resulted in resistance to cycloheximide, chloramphenicol and other drugs, such as the antifungal miconazole, with collateral hypersensitivity to oligomycin, nystatin and 2,4 dinitrophenol. Cycloheximide ATP-binding cassette multidrug transporter PDR5 Saccharomyces cerevisiae S288C