Title : Pathogenetic studies of hexane and carbon disulfide neurotoxicity.

Pub. Date : 1995

PMID : 7612176






1 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Both HD and CS2 react with protein amino functions to yield initial adducts (pyrrolyl or dithiocarbamate derivatives, respectively), which then undergo oxidation or decomposition to an electrophile (oxidized pyrrole ring or isothiocyanate), that then reacts with protein nucleophiles to result in protein cross-linking. Dithiocarbamate chorionic somatomammotropin hormone 2 Homo sapiens